HARRIS NOT NO BALLS AND JOE HAS NO BRAINS!!! WE ARE SCREWED ... WILL BE IN A WAR WITHIN A YEAR OR PERHAPS AMERICA WILL JUST ROLL OVER AND PLAY DEAD!
Wednesday, March 31, 2021
IVERMECTIN IS USED WITH HORSES ... BUT HAS BEEN REMOVED FROM SHELVES -- DUH!!!
TRACTOR SUPPLY HAS REMOVED IVERMECTIN FROM THEIR SHELVES ... THE COST OF BUYING IT IS SO INEXPENSIVE THAT PHARMA CAN NOT MAKE ANY MONEY!!! NOW THAT'S A GOOD REASON TO REMOVE IT FROM PUBLIC ACCESS. BECAUSE IT WORKS!!!
Ivermectin is a minor cytochrome P 3A4 substrate and a p-glycoprotein substrate. Ivermectin is generally given on an empty stomach with water; however, administering ivermectin with food increases its bioavailability. The FDA issued a warning in April 2020 that ivermectin intended for use in animals should not be used to treat COVID-19 in humans.
Tuesday, March 30, 2021
Monday, March 29, 2021
ESCAPE VELOCITY, PRESS CONFERENCE SHUFFLE, AND A LAP DOG
The search for intelligent life in Washington, D.C. -- main-stream media refusal to look beyond their ignorance, prejudice, or closed-mindedness-- not to mention their survival instinct of selected interest. The real search borders upon the speculation of an advanced civilization exist beyond the Beltway. After Biden's Press Show there is observational evidence we the citizens are alone!
MERRY-GO-ROUND, CANDY CORN, AND THE HOUSE OF HYPOCRITES
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Friday, March 26, 2021
WILL BIDEN MAKE IT TO APRIL 29, 2021 BEFORE THE 25TH IS INVOKED?
APRIL 29, 2021 IS 100 DAYS ... WILL BIDEN MAKE IT?
WE NEED A NATIONAL POOL ON WHETHER SLEEPY JOE WILL MAKE IT 100 DAYS ...
CLINTON FOUNDATION, CDC, AND A CUBAN CIGAR
CDC is a Private Organization – Not Government!
THIS IS A SMOKE-FREE ENVIRONMENT!
Some people have questioned my concern over both the CDC and John Hopkins University is a PRIVATE organization where the CDC accepts private funding – NOT ONLY GOVERNMENT! The CDC is quasi-government under the Department of Health and Human Services which strangely has sources of funding that are predicated on the fact that it also has a private 501(c)(3) public charity, like the Clinton Foundation. The CDC Foundation receives charitable contributions and philanthropic grants from individuals, foundations, corporations, universities, NGOs and other organizations to advance the work of the Centers for Disease Control and Prevention. This is NOT a government-funded organization. It is not exclusively government-funded – very curious.
I have serious questions as to what is being driven by the CDC in conjunction with John Hopkins University who takes $1.8 billion from Bloomberg. The CDC and John Hopkins are either deliberately trying to create an economic depression, or are sublimely ignorant of the consequences of their scorched earth policy. Yes, we can cure contagions by sequestering everyone and shutting down the economy. We all then live on handouts from the government, stay home, don’t work, and watch TV? As one reader commented: “Mirror, Mirror, on the wall; Guess we are all socialists after all!” "Is that a gun in your pocket or are you just offering me a cuban cigar? Well it really doesn't matter you're get F%^K in any event!"
Thursday, March 25, 2021
VACCINE PASSPORT ... HIPPA NO LONGER EXISTS?
A DIGITAL VACCINE PASSPORT ... FULL ACCESS TO YOUR PERSONAL HEALTH DATA ... I DON'T THINK SO! THERE ARE EXISTING LAWS AGAINST THIS ACCESS, WELL IF YOU BELIEVE THAT WANT TO HELP BUYING A BRIDGE IN BROOKLYN? ... CHECK THIS TO SEE JUST HOW MUCH PRIVACY YOU HAVE!!!
HIPAA BREACH NOTIFICATION RULE
The HIPAA Breach Notification Rule requires covered entities to notify affected individuals; HHS;
and, in some cases, the media of a breach of unsecured PHI. Generally, a breach is an impermissible use or disclosure under the Privacy Rule that compromises the security or privacy of PHI.
The impermissible use or disclosure of PHI is presumed to be a breach unless you demonstrate there is a low probability the PHI has been compromised based on a risk assessment of at least the following factors:
● The unauthorized person who used the PHI or to whom the disclosure was made
● Whether the PHI was actually acquired or viewed
● The extent to which the risk to the PHI has been mitigated.
Most notifications must be provided without unreasonable delay and no later than 60 days following the breach discovery. Notifications of smaller breaches affecting fewer than 500 individuals may be submitted to HHS annually. The Breach Notification Rule also requires business associates of covered entities to notify the covered entity of breaches at or by the business associate.
Visit the HHS HIPAA Breach Notification Rule webpage for guidance on:
● Administrative requirements and burden of proof● How to make unsecured PHI unusable, unreadable, or indecipherable to unauthorized individuals
● Reporting requirements
WHO MUST COMPLY WITH HIPAA RULES?
Covered entities and business associates, as applicable, must follow HIPAA rules. If an entity does not meet the definition of a covered entity or business associate, it does not have to comply with the HIPAA rules. For the definitions of “covered entity” and “business associate,” see the Code of FederalRegulations (CFR) Title 45, Section 160.103.
Covered Entities
The following covered entities must follow HIPAA standards and requirements:
● Covered Health Care Provider: Any provider of medical or other health care services or supplies who transmits any health information in electronic form in connection with a transaction for which HHS has adopted a standard, such as:
● Nursing homes Pharmacies Psychologists
● Health Plan: Any individual or group plan that provides or pays the cost of health care, such as: Company health plans Health insurance companies
Government programs that pay Health maintenance organizations (HMOs) for health care, such as Medicare, Medicaid, and the military and veterans’ health care programs
● Health Care Clearinghouse: A public or private entity that processes another entity’s health care transactions from a standard format to a non-standard format, or vice versa, such as:
● Billing services Repricing companies
● Community health management Value-added networks information systems
Wednesday, March 24, 2021
DID THE CDC A PRIVATE COMPANY LIE TO THE AMERICAN PUBLIC
BEFORE READING CLICK ON THE WORD VACCINE IN BLUE
Authorized and Recommended Vaccine
As COVID-19 vaccines are authorized and then recommended for use in the United States, it will be important to understand what is known about each vaccine.CDC will provide information on who is and is not recommended to receive each vaccine and what to expect after vaccination, as well as ingredients, safety, and effectiveness.
Currently, three vaccines are authorized and recommended to prevent COVID-19:
Vaccine Types
- Understanding How COVID-19 Vaccines Work
Learn how the body fights infection and how COVID-19 vaccines protect people by producing immunity. Also see the different types of COVID-19 vaccines that currently are available or are undergoing large-scale (Phase 3) clinical trials in the United States. - COVID-19 mRNA Vaccines
Information about mRNA vaccines generally and COVID-19 vaccines that use this new technology specifically. - Viral Vector COVID-19 Vaccines
Information about viral vector vaccines generally and COVID-19 vaccines that use this new technology specifically.
Vaccines in Phase 3 Clinical Trials
As of February 27, 2021, large-scale (Phase 3) clinical trials are in progress or being planned for two COVID-19 vaccines in the United States:
- AstraZeneca COVID-19 vaccine
- Novavax COVID-19 vaccine
Learn more about U.S. COVID-19 vaccine clinical trials, including vaccines in earlier stages of development, by visiting clinicaltrials.gov.
This page will be updated as additional information is available.
Tuesday, March 23, 2021
WORKING WITHOUT A NET OR A MEMORIAL OF HUMANITY
In a society dominated by faux privacy driven by consumerism, there are different kinds of value that can attach to a thing. First, there's functional, or use value: simply, what you can do with an object. The difference between use-value and exchange-value has some pertinence. Certainly, for a time, the Federal Reserve was able to provide a relatively plausible explanation of the growth of capitalism using just these categories. The use-value of an object would be it's utility-related in terms of the satisfaction of certain needs; exchange-value, on the other hand, would refer to the market value of a product, or object measured by its price. The object of exchange-value is International Trade of the commodity form of the object. The exchange-value, what an object is worth in terms of other objects. There's symbolic value, the value that one person places on an object in relation to another person. Finally, there's sign value, the value an object has within a system of other objects. But people are not mere objects or receptacles of symbolic cultural value.
"That life is a constant, zero-sum competition, and if you are not beating someone then someone is beating you. (The lesson of sports and game shows.) That the best response to any controversy or crisis is to heighten the conflict. (The lesson of TV news.) That people perform best when set to fight against one another for survival. (The lesson of The Apprentice.) That there is no history or objective truth beyond your immediate situational interests, and that reality resets with every tweet or click of the remote." ....................Donald J. Trump
WHAT DID THEY KNOW AND WHEN DID THEY KNOW IT!?
TIMING IS EVERYTHING ... THIS EVENT 201 WAS AN OUTGROWTH OF AGENDA 21 "THE SKY IS FALLING EVENT" ... COVID-19 TIMELINE WHO WHAT WHEN
EVENT 201: Coronavirus crisis is ushering in a new world order — and it was all planned out in the fall of 2019 ... but I dare say earlier.
This pandemic is a socialist wet dream come true
The coronavirus pandemic has led to a devastating shutdown of our economy, our businesses, and our way of life. It's everything socialists all over the world have dreamed of — an opportunity born out of crisis. But who drafted the agenda for our response to the pandemic?
Selected moments from the Event 201 pandemic tabletop exercise hosted by The Johns Hopkins Center for Health Security in partnership with the World Economic Forum and the Bill and Melinda Gates Foundation on October 18, 2019, in New York, NY. The exercise illustrated the pandemic preparedness efforts needed to diminish the large-scale economic and societal consequences of a severe pandemic. Drawing from actual events, Event 201 identifies important policy issues and preparedness challenges that could be solved with sufficient political will and attention. These issues were designed in a narrative to engage and educate the participants and the audience.
Wednesday, March 17, 2021
WHAT YOU DON'T KNOW WILL ... AND THE MAIN STREAM MEDIA DOESN'T KNOW --- OR DO THEY!?
BEFORE YOU SPEND THE TIME TO READ AND LISTEN PLEASE CHECK WHO GEERT VANDEN BOSSCHE, DMV, PhD IS ... https://www.linkedin.com/in/geertvandenbossche/ THEN DON'T DISMISS THIS POST ... WHAT YOU WILL LEARN WILL SHOCK YOU! ERRORS OF COMMISSION AND OMISSION ARE THE GREAT UNDERPINNING OF THE MARKETING OF EVIL!
The Great Barrington Declaration
The Great Barrington Declaration – As infectious disease epidemiologists and public health scientists we have grave concerns about the damaging physical and mental health impacts of the prevailing COVID-19 policies, and recommend an approach we call Focused Protection.
Coming from both the left and right, and around the world, we have devoted our careers to protecting people. Current lockdown policies are producing devastating effects on short and long-term public health. The results (to name a few) include lower childhood vaccination rates, worsening cardiovascular disease outcomes, fewer cancer screenings and deteriorating mental health – leading to greater excess mortality in years to come, with the working class and younger members of society carrying the heaviest burden. Keeping students out of school is a grave injustice.
Keeping these measures in place until a vaccine is available will cause irreparable damage, with the underprivileged disproportionately harmed.
Fortunately, our understanding of the virus is growing. We know that vulnerability to death from COVID-19 is more than a thousand-fold higher in the old and infirm than the young.
Indeed, for children, COVID-19 is less dangerous than many other harms, including influenza.
As immunity builds in the population, the risk of infection to all – including the vulnerable – falls. We know that all populations will eventually reach herd immunity – i.e. the point at which the rate of new infections is stable – and that this can be assisted by (but is not dependent upon) a vaccine. Our goal should therefore be to minimize mortality and social harm until we reach herd immunity.
The most compassionate approach that balances the risks and benefits of reaching herd immunity, is to allow those who are at minimal risk of death to live their lives normally to build up immunity to the virus through natural infection, while better protecting those who are at highest risk. We call this Focused Protection.
Adopting measures to protect the vulnerable should be the central aim of public health responses to COVID-19. By way of example, nursing homes should use staff with acquired immunity and perform frequent testing of other staff and all visitors. Staff rotation should be minimized. Retired people living at home should have groceries and other essentials delivered to their home. When possible, they should meet family members outside rather than inside. A comprehensive and detailed list of measures, including approaches to multi-generational households, can be implemented, and is well within the scope and capability of public health professionals.
Those who are not vulnerable should immediately be allowed to resume life as normal. Simple hygiene measures, such as hand washing and staying home when sick should be practiced by everyone to reduce the herd immunity threshold. Schools and universities should be open for in-person teaching.
Extracurricular activities, such as sports, should be resumed. Young low-risk adults should work normally, rather than from home. Restaurants and other businesses should open. Arts, music, sport and other cultural activities should resume. People who are more at risk may participate if they wish, while society as a whole enjoys the protection conferred upon the vulnerable by those who have built up herd immunity.
WELL, I'M GLAD YOU MADE IT THIS FAR ... NOW CLICK ON THE VIDEO AND WHAT YOU WILL LEARN WILL, I REPEAT WILL SCARE THE HELL OUT OF YOU!
Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, formerly employed at GAVI and The Bill & Melinda Gates Foundation.
To all authorities, scientists and experts around the world, to whom this concerns: the entire world population.
I am all but an antvaxxer. As a scientist, I do not usually appeal to any platform of this kind to make a stand on vaccine-related topics. As a dedicated virologist and vaccine expert, I only make an exception when health authorities allow vaccines to be administered in ways that threaten public health, most certainly when scientific evidence is being ignored. The present extremely critical situation forces me to spread this emergency call. As the unprecedented extent of human intervention in the Covid-19- pandemic is now at risk of resulting in a global catastrophe without equal, this call cannot sound loudly and strongly enough.
As stated, I am not against vaccination. On the contrary, I can assure you that each of the current vaccines have been designed, developed and manufactured by brilliant and competent scientists. However, this type of prophylactic vaccines are completely inappropriate, and even highly dangerous, when used in mass vaccination campaigns during a viral pandemic. Vaccinologists, scientists and clinicians are blinded by the positive short-term effects in individual patients, but don’t seem to bother about the disastrous consequences for global health. Unless I am scientifically proven wrong, it is difficult to understand how current human interventions will prevent circulating variants from turning into a wild monster.
Racing against the clock, I am completing my scientific manuscript, the publication of which is, unfortunately, likely to come too late given the ever-increasing threat from rapidly spreading, highly infectious variants. This is why I decided to already post a summary of my findings as well as my keynote speech at the recent Vaccine Summit in Ohio on LinkedIn. Last Monday, I provided international health organizations, including the WHO, with my analysis of the current pandemic as based on scientifically informed insights in the immune biology of Covid-19. Given the level of emergency, I urged them to consider my concerns and to initiate a debate on the detrimental consequences of further ‘viral immune escape’. For those who are no experts in this field, I am attaching below a more accessible and comprehensible version of the science behind this insidious phenomenon.
While there is no time to spare, I have not received any feedback thus far. Experts and politicians have remained silent while obviously still eager to talk about relaxing infection prevention rules and 'springtime freedom'. My statements are based on nothing else but science. They shall only be contradicted by science. While one can barely make any incorrect scientific statements without being criticized by peers, it seems like the elite of scientists who are currently advising our world leaders prefer to stay silent. Sufficient scientific evidence has been brought to the table. Unfortunately, it remains untouched by those who have the power to act. How long can one ignore the problem when there is at present massive evidence that viral immune escape is now threatening humanity? We can hardly say we didn't know - or were not warned.
In this agonizing letter I put all of my reputation and credibility at stake. I expect from you, guardians of mankind, at least the same. It is of utmost urgency. Do open the debate. By all means: turn the tide!
Author: Geert Vanden Bossche, DVM, PhD (March 6, 2021) – https://www.linkedin.com/in/geertvandenbossche/
PUBLIC HEALTH EMERGENCY OF INTERNATIONAL CONCERN
Why mass vaccination amidst a pandemic creates an irrepressible monster
THE key question is: why does nobody seem to bother about viral immune escape? Let me try to explain this by means of a more easily understood phenomenon: Antimicrobial resistance. One can easily extrapolate this scourge to resistance to our self-made ‘antiviral antibiotics. Indeed, antibodies (Abs) produced by our own immune system can be considered self-made antiviral antibiotics, regardless of whether they are part of our innate immune system (so-called ‘natural’ Abs’) or elicited in response to specific pathogens (resulting in so-called ‘acquired’ Abs). Natural Abs are not germ-specific whereas acquired Abs are specifically directed at the invading pathogen. At birth, our innate immune system is ‘unexperienced’ but well-established. It protects us from a multitude of pathogens, thereby preventing these pathogens from causing disease. As the innate immune system cannot remember the pathogens it encountered (innate immunity has no so-called ‘immunological memory’), we can only continue to rely on it provided we keep it ‘trained’ well enough. Training is achieved by regular exposure to a myriad of environmental agents, including pathogens. However, as we age, we will increasingly face situations where our innate immunity (often called ‘the first line of immune defense’) is not strong enough to halt the pathogen at the portal of entry (mostly mucosal barriers like respiratory or intestinal epithelial). When this happens, the immune system has to rely on more specialized effectors of our immune system (i.e., antigen-specific Abs and T cells) to fight the pathogen. So, as we grow up, we increasingly mount pathogen-specific immunity, including highly specific Abs. As those have a stronger affinity for the pathogen (e.g., virus) and can reach high concentrations, they can quite easily outcompete our natural Abs for binding to the pathogen/virus. It is precisely this type of highly specific, high affinity Abs that current Covid-19 vaccines are inducing. Of course, the noble purpose of these Abs is to protect us against Covid-19. So, why then should there be a major concern using these vaccines to fight Covid-19?
Well, similar to the rules applying to classical antimicrobial antibiotics, it is paramount that our self-made ‘antiviral antibiotics are made available in sufficient concentration and are tailored at the specific features of our enemy. This is why in case of bacterial disease it is critical to not only chose the right type of antibiotic (based on the results from an antibiogram) but to also take the antibiotic for long enough (according to the prescription). Failure to comply with these requirements is at risk of granting microbes a chance to survive and hence, may cause the disease to fare up. A very similar mechanism may also apply to viruses, especially to viruses that can easily and rapidly mutate (which is, for example, the case with Coronaviruses); when the pressure exerted by the army’s (read: population's) immune defense starts to threaten viral replication and transmission, the virus will take on another coat so that it can no longer be easily recognized and, therefore, attacked by the host immune system. The virus is now able to escape immunity (so-called: ‘immune escape’). However, the virus can only rely on this strategy provided it still has room enough to replicate. Viruses, in contrast to the majority of bacteria, must rely on living host cells to replicate. This is why the occurrence of ‘escape mutants’ isn’t too worrisome as long as the likelihood for these variants to rapidly find another host is quite remote. However, that’s not particularly the case during a viral pandemic! During a pandemic, the virus is spreading all over the globe with many subjects shedding and transmitting the virus (even including asymptomatic ‘carriers’). The higher the viral load, the higher the likelihood for the virus to bump into subjects who haven’t been infected yet or who were infected but didn’t develop symptoms. Unless they are sufficiently protected by their innate immune defense (through natural Abs), they will catch Covid-19 disease as they cannot rely on others, i.e., acquired Abs. It has been extensively reported, indeed, that the increase in S (spike)-specific Abs in
Author: Geert Vanden Bossche, DVM, PhD (March 6, 2021) – https://www.linkedin.com/in/geertvandenbossche/
asymptomatically infected people is rather limited and only short-lived. Furthermore, these Abs have not achieved full maturity. The combination of viral infection on a background of suboptimal Ab maturity and concentration enables the virus to select mutations allowing it to escape the immune pressure. The selection of those mutations preferably occurs in the S protein as this is the viral protein that is responsible for viral infectiousness. As the selected mutations endow the virus with increased infectious capacity, it now becomes much easier for the virus to cause severe disease in infected subjects. The more people develop the symptomatic disease, the better the virus can secure its propagation and perpetuation (people who get the severe disease will shed more virus and for a longer period of time than asymptomatically infected subjects do). Unfortunately enough, the short-lived rise in S-specific Abs does, however, suffice to bypass people’s innate/natural Ab. Those are put out of business as their affinity for S is lower than the affinity of S-specific Abs. This is to say that with an increasing rate of infection in the population, the number of subjects who get infected while experiencing a momentary increase in S- specific Abs will steadily increase. Consequently, the number of subjects who get infected while experiencing a momentary decrease in their innate immunity will increase. As a result, a steadily increasing number of subjects will become more susceptible to getting severe disease instead of showing only mild symptoms (i.e., limited to the upper respiratory tract) or no symptoms at all. During a pandemic, especially youngsters will be affected by this evolution as their natural Abs are not yet largely suppressed by a panoply of ‘acquired’, antigen-specific Abs. Natural Abs, and natural immunity in general, play a critical role in protecting us from pathogens as they constitute our first line of immune defense. In contrast to acquired immunity, innate immune responses protect against a large spectrum of pathogens (so don’t compromise or sacrifice your innate immune defense!). Because natural Abs and innate immune cells recognize a diversified spectrum of foreign (i.e., non-self) agents (only some of which have pathogenic potential), it’s important, indeed, to keep it sufficiently exposed to environmental challenges. By keeping the innate immune system (which, unfortunately, has no memory!) TRAINED, we can much more easily resist germs that have real pathogenic potential. It has, for example, been reported and scientifically proved that exposure to other, quite harmless Coronaviruses causing a ‘common cold ’ can provide protection, although short-lived, against Covid-19 and its loyal henchmen (i.e., the more infectious variants).
Suppression of innate immunity, especially in the younger age groups, can, therefore, become very problematic. There can be no doubt that lack of exposure due to stringent containment measures implemented as of the beginning of the pandemic has not been beneficial to keeping people’s innate immune system well trained. As if this was not already heavily compromising innate immune defense in this population segment, there comes yet another force into play that will dramatically enhance morbidity and mortality rates in the younger age groups: MASS VACCINATION of the ELDERLY. The more extensively the later age group will be vaccinated and hence, protected, the more the virus is forced to continue causing disease in younger age groups. This is only going to be possible provided it escapes to the S-specific Abs that are momentarily raised in previously asymptomatically infected subjects. If the virus manages to do so, it can benefit from the (momentarily) suppressed innate immunity, thereby causing disease in an increasing number of these subjects and ensuring its own propagation. Selecting targeted mutations in the S protein is, therefore, the way to go in order for the virus to enhance its infectiousness in candidates that are prone to getting the disease because of a transient weakness of their innate immune defense.
But in the meantime, we’re also facing a huge problem in vaccinated people as they’re now more and more confronted with infectious variants displaying a type of S protein that is increasingly different from
Author: Geert Vanden Bossche, DVM, PhD (March 6, 2021) – https://www.linkedin.com/in/geertvandenbossche/
the S edition comprised within the vaccine (the later edition originates from the original, much less infectious strain at the beginning of the pandemic). The more variants become infectious (i.e., as a result of blocking access of the virus to the vaccinated segment of the population), the less vaccinal Abs will protect. Already now, lack of protection is leading to viral shedding and transmission in vaccine recipients who are exposed to these more infectious strains (which, by the way, increasingly dominate the field). This is how we are currently turning vaccinees into asymptomatic carriers shedding infectious variants.
At some point, in a likely very near future, it’s going to become more profitable (in term of ‘return on selection investment’) for the virus to just add another few mutations (maybe just one or two) to the S protein of viral variants (already endowed with multiple mutations enhancing infectiousness) in an attempt to further strengthen its binding to the receptor (ACE-2) expressed on the surface of permissive epithelial cells. This will now allow the new variant to outcompete vaccinal Abs for binding to the ACE receptor. This is to say that at this stage, it would only take very few additional targeted mutations within the viral receptor-binding domain to fully resist S-specific ant-Covid-19 Abs, regardless whether the latter are elicited by the vaccine or by natural infection. At that stage, the virus will, indeed, have managed to gain access to a huge reservoir of subjects who have now become highly susceptible to disease as their S-specific Abs have now become useless in terms of protection but stll manage to provide for long-lived suppression of their innate immunity (i.e., natural infection, and especially vaccination, elicit relatively long-lived specific Ab titers). The susceptible reservoir comprises both, vaccinated people and those who’re left with sufficient S-specific Abs due to previous Covid-19 disease). So, MISSION ACCOMPLISHED for Covid-19 but a DISASTROUS SITUATION for all vaccinated subjects and Covid-19 seropositive people as they’ve now lost both, their acquired and innate immune defense against Covid-19 (while highly infectious strains are circulating!). That’s ‘one small step for the virus, one giant catastrophe for mankind’, which is to say that we’ll have whipped up the virus in the younger population up to a level that it now takes little effort for Covid-19 to transform into a highly infectious virus that completely ignores both the innate arm of our immune system as well as the adaptive/acquired one (regardless of whether the acquired Abs resulted from vaccination or natural infection). The effort for the virus is now becoming even more negligible given that many vaccine recipients are now exposed to highly infectious viral variants while having received only a single shot of the vaccine. Hence, they are endowed with Abs that have not yet acquired optimal functionality. There is no need to explain that this is just going to further enhance immune escape. Basically, we’ll very soon be confronted with a super-infectious virus that completely resists our most precious defense mechanism: The human immune system.
From all of the above, it’s becoming increasingly difficult to imagine how the consequences of the extensive and erroneous human intervention in this pandemic are not going to wipe out large parts of our human population. One could only think of very few other strategies to achieve the same level of efficiency in turning a relatively harmless virus into a bioweapon of mass destruction.
It’s certainly also worth mentioning that mutations in the S protein (i.e., exactly the same protein that is subject to selection of escape mutations) are known to enable Coronaviruses to cross species barriers. This is to say that the risk that vaccine-mediated immune escape could allow the virus to jump to other animal species, especially industrial livestock (e.g., pig and poultry farms), is not negligible. These species are already known to host several different Coronaviruses and are usually housed in farms with high stocking density. Similar to the situation with influenza virus, these species could than serve as an
Author: Geert Vanden Bossche, DVM, PhD (March 6, 2021) – https://www.linkedin.com/in/geertvandenbossche/
additional reservoir for SARS-COVID-2 virus.
As pathogens have co-evolved with the host immune system, natural pandemics of acute self-limiting viral infections have been shaped such as to take a toll on human lives that is not higher than strictly required. Due to human intervention, the course of this pandemic has been thoroughly disturbed as of the very beginning. Widespread and stringent infection prevention measures combined with mass vaccination campaigns using inadequate vaccines will undoubtedly lead to a situation where the pandemic is getting increasingly ‘out of control’.
Paradoxically, the only intervention that could offer a perspective to end this pandemic (other than to let it run its disastrous course) is ...VACCINATION. Of course, the type of vaccines to be used would be completely different from conventional vaccines in that they’re not inducing the usual suspects, i.e., B and T cells, but NK cells. There is, indeed, compelling scientific evidence that these cells play a key role in facilitating complete elimination of Covid-19 at an early stage of infection in asymptomatically infected subjects. NK cells are part of the cellular arm of our innate immune system and, alike natural Abs, they are capable of recognizing and attacking a broad and diversified spectrum of pathogenic agents. There is a sound scientific rationale to assume that it is possible to ‘prime’ NK cells in ways for them to recognize and kill Coronaviruses at large (include all their variants) at an early stage of infection. NK cells have increasingly been described to be endowed with the capacity to acquire immunological memory. By educating these cells in ways that enable them to durably recognize and target Coronavirus-infected cells, our immune system could be perfectly armed for a targeted atack to the universe of Coronaviruses prior to exposure. As NK cell-based immune defense provides sterilizing immunity and allows for broad-spectrum and fast protection, it is reasonable to assume that harnessing our innate immune cells is going to be the only type of human intervention left to halt the dangerous spread of highly infectious Covid-19 variants.
If we, human beings, are committed to perpetuating our species, we have no choice left but to eradicate these highly infectious viral variants. This will, indeed, require large vaccination campaigns. However, NK cell-based vaccines will primarily enable our natural immunity to be better prepared (memory!) and to induce herd immunity (which is exactly the opposite of what current Covid-19 vaccines do as those increasingly turn vaccine recipients into asymptomatic carriers who are shedding virus). So, there is not one-second left for gears to be switched and to replace the current killer vaccines by life-saving vaccines.
I am appealing to the WHO and all stakeholders involved, no matter their conviction, to immediately declare such acton as THE SINGLE MOST IMPORTANT PUBLIC HEALTH EMERGENCY OF INTERNATIONAL CONCERN.
Author: Geert Vanden Bossche, DVM, PhD (March 6, 2021) – https://www.linkedin.com/in/geertvandenbossche/
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